Hypocretin/orexin prevents recovery from sickness
نویسندگان
چکیده
منابع مشابه
Molecular Hydrogen Reduces LPS-Induced Neuroinflammation and Promotes Recovery from Sickness Behaviour in Mice
Molecular hydrogen has been shown to have neuroprotective effects in mouse models of acute neurodegeneration. The effect was suggested to be mediated by its free-radical scavenger properties. However, it has been shown recently that molecular hydrogen alters gene expression and protein phosphorylation. The aim of this study was to test whether chronic ad libitum consumption of molecular hydroge...
متن کاملOvariectomy prevents the recovery of atrophied gastrocnemius skeletal muscle mass.
The recovery of atrophied muscle mass in animals is thought to be dependent on a number of factors including hormones, cytokines, and/or growth factor expression. The Akt/mammalian target of rapamycin (mTOR) signaling pathway is believed to be activated by these various factors, resulting in skeletal muscle growth through the initiation of protein synthesis. It was hypothesized that surgical re...
متن کاملFasudil prevents KATP channel-induced improvement in postischemic functional recovery.
Whereas activation of ATP-dependent potassium (K(ATP)) channels greatly improves postischemic myocardial recovery, the final effector mechanism for K(ATP) channel-induced cardioprotection remains elusive. RhoA is a GTPase that regulates a variety of cellular processes known to be involved with K(ATP) channel cardioprotection. Our goal was to determine whether the activity of a key rhoA effector...
متن کاملFalling towards Forgetfulness: Synaptic Decay Prevents Spontaneous Recovery of Memory
Long after a new language has been learned and forgotten, relearning a few words seems to trigger the recall of other words. This "free-lunch learning" (FLL) effect has been demonstrated both in humans and in neural network models. Specifically, previous work proved that linear networks that learn a set of associations, then partially forget them all, and finally relearn some of the association...
متن کاملDeath from Compressed-Air Sickness in India
disease of a man working on the river Hooghly Tunnel being constructed by Messrs. John Cochrane & Sons, Ltd., of Westminster, London, is of special interest as it is probably the first report of & deatfy from this disease in India. C. S., a Punjabi Sikh, aged 20 years, was medically examined on the 25th August, 1930, in the morning and was found fit. for work in " compressed air." He reported h...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Biomedical Reports
سال: 2015
ISSN: 2049-9434,2049-9442
DOI: 10.3892/br.2015.491